Entity Details

Primary name MP2K7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14733
EntryNameMP2K7_HUMAN
FullNameDual specificity mitogen-activated protein kinase kinase 7
TaxID9606
Evidenceevidence at protein level
Length419
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesMAP2K7

GO terms

Show/Hide Table
GOName
GO:0000187 obsolete activation of MAPK activity
GO:0000287 magnesium ion binding
GO:0004708 MAP kinase kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006970 response to osmotic stress
GO:0007165 signal transduction
GO:0007254 JNK cascade
GO:0007257 obsolete activation of JUN kinase activity
GO:0008545 JUN kinase kinase activity
GO:0009408 response to heat
GO:0009411 response to UV
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0034612 response to tumor necrosis factor
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:0051403 stress-activated MAPK cascade
GO:0051973 positive regulation of telomerase activity
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1904355 positive regulation of telomere capping

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
MP2K7_HUMANDUS22_MOUSEBioGRID12138158 details