Entity Details

Primary name ANM5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14744
EntryNameANM5_HUMAN
FullNameProtein arginine N-methyltransferase 5
TaxID9606
Evidenceevidence at protein level
Length637
SequenceStatuscomplete
DateCreated2003-06-20
DateModified2021-06-02

Ontological Relatives

GenesPRMT5

GO terms

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GOName
GO:0000387 spliceosomal snRNP assembly
GO:0000785 chromatin
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006353 DNA-templated transcription, termination
GO:0006355 regulation of transcription, DNA-templated
GO:0007088 regulation of mitotic nuclear division
GO:0008168 methyltransferase activity
GO:0008327 methyl-CpG binding
GO:0008469 histone-arginine N-methyltransferase activity
GO:0016274 protein-arginine N-methyltransferase activity
GO:0018216 peptidyl-arginine methylation
GO:0032922 circadian regulation of gene expression
GO:0034709 methylosome
GO:0034969 histone arginine methylation
GO:0035097 histone methyltransferase complex
GO:0035243 protein-arginine omega-N symmetric methyltransferase activity
GO:0035246 peptidyl-arginine N-methylation
GO:0042118 endothelial cell activation
GO:0042802 identical protein binding
GO:0043021 ribonucleoprotein complex binding
GO:0043985 histone H4-R3 methylation
GO:0044020 histone methyltransferase activity (H4-R3 specific)
GO:0044030 regulation of DNA methylation
GO:0045596 negative regulation of cell differentiation
GO:0046982 protein heterodimerization activity
GO:0048714 positive regulation of oligodendrocyte differentiation
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:0070888 E-box binding
GO:0090161 Golgi ribbon formation
GO:0097421 liver regeneration
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1904992 positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Golgi apparatus
Nucleus

Domains

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DomainNameCategoryType
IPR007857 Protein arginine N-methyltransferase PRMT5FamilyFamily
IPR025799 Protein arginine N-methyltransferaseFamilyFamily
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily
IPR035075 PRMT5 arginine-N-methyltransferaseDomainDomain
IPR035247 PRMT5, TIM barrel domainDomainDomain
IPR035248 PRMT5, oligomerisation domainDomainDomain

Diseases

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Interactions

3 interactions