Entity Details

Primary name GNB5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14775
EntryNameGNB5_HUMAN
FullNameGuanine nucleotide-binding protein subunit beta-5
TaxID9606
Evidenceevidence at protein level
Length395
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesGNB5

GO terms

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GOName
GO:0003924 GTPase activity
GO:0005096 GTPase activator activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005834 heterotrimeric G-protein complex
GO:0006457 protein folding
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007212 dopamine receptor signaling pathway
GO:0031682 G-protein gamma-subunit binding
GO:0043547 positive regulation of GTPase activity
GO:0051087 chaperone binding
GO:0098793 presynapse
GO:1901386 negative regulation of voltage-gated calcium channel activity
GO:1902773 GTPase activator complex

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR001632 G-protein, beta subunitDomainDomain
IPR001680 WD40 repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016346 Guanine nucleotide-binding protein, beta subunitFamilyFamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR020472 G-protein beta WD-40 repeatRepeatRepeat
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GNB5_HUMANUBP19_MOUSEIntAct25036637 details