Entity Details

Primary name CSKP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14936
EntryNameCSKP_HUMAN
FullNamePeripheral plasma membrane protein CASK
TaxID9606
Evidenceevidence at protein level
Length926
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesCASK

GO terms

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GOName
GO:0001953 negative regulation of cell-matrix adhesion
GO:0004385 guanylate kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005604 basement membrane
GO:0005652 nuclear lamina
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005925 focal adhesion
GO:0006836 neurotransmitter transport
GO:0007155 cell adhesion
GO:0010839 negative regulation of keratinocyte proliferation
GO:0015629 actin cytoskeleton
GO:0016363 nuclear matrix
GO:0042734 presynaptic membrane
GO:0060170 ciliary membrane
GO:0061045 negative regulation of wound healing
GO:0090288 negative regulation of cellular response to growth factor stimulus
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR004172 L27 domainDomainDomain
IPR008144 Guanylate kinase-like domainDomainDomain
IPR008145 Guanylate kinase/L-type calcium channel beta subunitDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR014775 L27 domain, C-terminalDomainDomain
IPR020590 Guanylate kinase, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR035473 CASK, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR036892 L27 domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01942 Formic acidDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CSKP_HUMANJAM1_MOUSEBioGRID11120739 details