Entity Details

Primary name XPO1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14980
EntryNameXPO1_HUMAN
FullNameExportin-1
TaxID9606
Evidenceevidence at protein level
Length1071
SequenceStatuscomplete
DateCreated2005-06-21
DateModified2021-06-02

Ontological Relatives

GenesXPO1

GO terms

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GOName
GO:0000054 ribosomal subunit export from nucleus
GO:0000055 ribosomal large subunit export from nucleus
GO:0000056 ribosomal small subunit export from nucleus
GO:0000776 kinetochore
GO:0003723 RNA binding
GO:0005049 nuclear export signal receptor activity
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005642 annulate lamellae
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006611 protein export from nucleus
GO:0006913 nucleocytoplasmic transport
GO:0007052 mitotic spindle organization
GO:0015030 Cajal body
GO:0016020 membrane
GO:0016032 viral process
GO:0031267 small GTPase binding
GO:0031965 nuclear membrane
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032991 protein-containing complex
GO:0042254 ribosome biogenesis
GO:0043231 intracellular membrane-bounded organelle
GO:0043488 regulation of mRNA stability
GO:0043657 host cell
GO:0051028 mRNA transport
GO:0075733 intracellular transport of virus
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001494 Importin-beta, N-terminal domainDomainDomain
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR013598 Exportin-1/Importin-beta-likeDomainDomain
IPR014877 Exportin-1, C-terminalDomainDomain
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR040485 Exportin-1, repeat 3RepeatRepeat
IPR041123 Chromosome region maintenance repeatRepeatRepeat
IPR041235 Exportin-1, repeat 2RepeatRepeat

Diseases

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Drugs

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DrugNameSourceType
DB11942 SelinexorDrugbanksmall molecule

Interactions

4 interactions