Entity Details

Primary name SET1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15047
EntryNameSET1A_HUMAN
FullNameHistone-lysine N-methyltransferase SETD1A
TaxID9606
Evidenceevidence at protein level
Length1707
SequenceStatuscomplete
DateCreated2005-06-21
DateModified2021-06-02

Ontological Relatives

GenesSETD1A

GO terms

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GOName
GO:0000785 chromatin
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0007420 brain development
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0016607 nuclear speck
GO:0035097 histone methyltransferase complex
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0044648 histone H3-K4 dimethylation
GO:0045652 regulation of megakaryocyte differentiation
GO:0048188 Set1C/COMPASS complex
GO:0080182 histone H3-K4 trimethylation
GO:0097692 histone H3-K4 monomethylation
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:1902275 regulation of chromatin organization

Subcellular Location

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Subcellular Location
Chromosome
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR001214 SET domainDomainDomain
IPR003616 Post-SET domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR024657 COMPASS complex Set1 subunit, N-SET domainDomainDomain
IPR034467 Set1A, RNA recognition motifDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily
IPR037841 Histone-lysine N-methyltransferase SETD1AFamilyFamily
IPR044570 Histone-lysine N-methyltransferase Set1-likeFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SET1A_HUMANCTNB1_MOUSEDIP22723415 details