Entity Details

Primary name DCLK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15075
EntryNameDCLK1_HUMAN
FullNameSerine/threonine-protein kinase DCLK1
TaxID9606
Evidenceevidence at protein level
Length740
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesDCLK1

GO terms

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GOName
GO:0001764 neuron migration
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0005887 integral component of plasma membrane
GO:0006468 protein phosphorylation
GO:0007399 nervous system development
GO:0007417 central nervous system development
GO:0009615 response to virus
GO:0014069 postsynaptic density
GO:0016197 endosomal transport
GO:0018105 peptidyl-serine phosphorylation
GO:0021952 central nervous system projection neuron axonogenesis
GO:0030900 forebrain development
GO:0035556 intracellular signal transduction
GO:0048675 axon extension
GO:0048812 neuron projection morphogenesis
GO:0048813 dendrite morphogenesis
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1900181 negative regulation of protein localization to nucleus

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR003533 Doublecortin domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR036572 Doublecortin domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule

Interactions

0 interactions

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