Entity Details

Primary name DEGS1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15121
EntryNameDEGS1_HUMAN
FullNameSphingolipid delta(4)-desaturase DES1
TaxID9606
Evidenceevidence at protein level
Length323
SequenceStatuscomplete
DateCreated2007-12-04
DateModified2021-06-02

Ontological Relatives

GenesDEGS1

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006636 unsaturated fatty acid biosynthetic process
GO:0009055 electron transfer activity
GO:0016020 membrane
GO:0030148 sphingolipid biosynthetic process
GO:0031966 mitochondrial membrane
GO:0035579 specific granule membrane
GO:0042284 sphingolipid delta-4 desaturase activity
GO:0043217 myelin maintenance
GO:0043312 neutrophil degranulation
GO:0046513 ceramide biosynthetic process
GO:0050251 retinol isomerase activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Mitochondrion membrane

Domains

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DomainNameCategoryType
IPR005804 Fatty acid desaturase domainDomainDomain
IPR011388 Sphingolipid delta4-desaturaseFamilyFamily
IPR013866 Sphingolipid delta4-desaturase, N-terminalDomainDomain
IPR031196 Sphingolipid delta(4)-desaturase DES1FamilyFamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink