Entity Details

Primary name MDM4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15151
EntryNameMDM4_HUMAN
FullNameProtein Mdm4
TaxID9606
Evidenceevidence at protein level
Length490
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesMDM4

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003170 heart valve development
GO:0003181 atrioventricular valve morphogenesis
GO:0003203 endocardial cushion morphogenesis
GO:0003281 ventricular septum development
GO:0003283 atrial septum development
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0008270 zinc ion binding
GO:0008285 negative regulation of cell population proliferation
GO:0016579 protein deubiquitination
GO:0019899 enzyme binding
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0042177 negative regulation of protein catabolic process
GO:0043066 negative regulation of apoptotic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050821 protein stabilization
GO:0065003 protein-containing complex assembly
GO:0071456 cellular response to hypoxia
GO:1901796 regulation of signal transduction by p53 class mediator

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR001876 Zinc finger, RanBP2-typeDomainDomain
IPR003121 SWIB/MDM2 domainDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR015458 MDM4FamilyFamily
IPR016495 p53 negative regulator Mdm2/Mdm4FamilyFamily
IPR036443 Zinc finger, RanBP2-type superfamilyFamilyHomologous superfamily
IPR036885 SWIB/MDM2 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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