Entity Details

Primary name BIRC5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15392
EntryNameBIRC5_HUMAN
FullNameBaculoviral IAP repeat-containing protein 5
TaxID9606
Evidenceevidence at protein level
Length142
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesBIRC5

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000228 nuclear chromosome
GO:0000278 mitotic cell cycle
GO:0000281 mitotic cytokinesis
GO:0000775 chromosome, centromeric region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005814 centriole
GO:0005829 cytosol
GO:0005876 spindle microtubule
GO:0005881 cytoplasmic microtubule
GO:0006468 protein phosphorylation
GO:0007052 mitotic spindle organization
GO:0007059 chromosome segregation
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0007605 sensory perception of sound
GO:0008017 microtubule binding
GO:0008270 zinc ion binding
GO:0008284 positive regulation of cell population proliferation
GO:0015631 tubulin binding
GO:0019221 cytokine-mediated signaling pathway
GO:0019899 enzyme binding
GO:0030496 midbody
GO:0031021 interphase microtubule organizing center
GO:0031267 small GTPase binding
GO:0031503 protein-containing complex localization
GO:0031536 positive regulation of exit from mitosis
GO:0032133 chromosome passenger complex
GO:0032991 protein-containing complex
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042981 regulation of apoptotic process
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045931 positive regulation of mitotic cell cycle
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0050897 cobalt ion binding
GO:0051087 chaperone binding
GO:0051301 cell division
GO:0051303 establishment of chromosome localization
GO:0051726 regulation of cell cycle

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Midbody
Nucleus

Domains

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DomainNameCategoryType
IPR001370 BIR repeatRepeatRepeat

Diseases

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Drugs

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DrugNameSourceType
DB00206 ReserpineDrugbanksmall molecule
DB04115 BerberineDrugbanksmall molecule
DB05141 LY2181308Drugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
BIRC5_HUMANBIRC6_MOUSEIntAct18329369 details