Entity Details

Primary name MOT4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15427
EntryNameMOT4_HUMAN
FullNameMonocarboxylate transporter 4
TaxID9606
Evidenceevidence at protein level
Length465
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesSLC16A3

GO terms

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GOName
GO:0003723 RNA binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006090 pyruvate metabolic process
GO:0008028 monocarboxylic acid transmembrane transporter activity
GO:0015129 lactate transmembrane transporter activity
GO:0015293 symporter activity
GO:0015718 monocarboxylic acid transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0031965 nuclear membrane
GO:0035879 plasma membrane lactate transport
GO:0050900 leukocyte migration
GO:0098688 parallel fiber to Purkinje cell synapse
GO:0099061 integral component of postsynaptic density membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR004743 Monocarboxylate transporterFamilyFamily
IPR011701 Major facilitator superfamilyFamilyFamily
IPR020846 Major facilitator superfamily domainDomainDomain
IPR030756 Monocarboxylate transporter 4FamilyFamily
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00119 Pyruvic acidDrugbanksmall molecule
DB00627 NiacinDrugbanksmall molecule
DB01440 gamma-Hydroxybutyric acidDrugbanksmall molecule
DB01762 Acetoacetic acidDrugbanksmall molecule
DB01942 Formic acidDrugbanksmall molecule
DB03066 D-Lactic acidDrugbanksmall molecule
DB03884 Phenylpyruvic acidDrugbanksmall molecule
DB03940 Oxamic AcidDrugbanksmall molecule
DB04074 alpha-KetoisovalerateDrugbanksmall molecule
DB04343 Glyoxylic acidDrugbanksmall molecule
DB04398 Lactic acidDrugbanksmall molecule

Interactions

0 interactions

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