Entity Details

Primary name INSI1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15503
EntryNameINSI1_HUMAN
FullNameInsulin-induced gene 1 protein
TaxID9606
Evidenceevidence at protein level
Length277
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesINSIG1

GO terms

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GOName
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006641 triglyceride metabolic process
GO:0006695 cholesterol biosynthetic process
GO:0008142 oxysterol binding
GO:0010894 negative regulation of steroid biosynthetic process
GO:0016126 sterol biosynthetic process
GO:0032869 cellular response to insulin stimulus
GO:0032933 SREBP signaling pathway
GO:0032937 SREBP-SCAP-Insig complex
GO:0036315 cellular response to sterol
GO:0036316 SREBP-SCAP complex retention in endoplasmic reticulum
GO:0042472 inner ear morphogenesis
GO:0042474 middle ear morphogenesis
GO:0042632 cholesterol homeostasis
GO:0045599 negative regulation of fat cell differentiation
GO:0045717 negative regulation of fatty acid biosynthetic process
GO:0060021 roof of mouth development
GO:0060363 cranial suture morphogenesis
GO:0070862 negative regulation of protein exit from endoplasmic reticulum
GO:1901303 negative regulation of cargo loading into COPII-coated vesicle

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR009904 Insulin-induced gene 1 proteinFamilyFamily
IPR025929 Insulin-induced protein familyFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
INSI1_HUMANSCAP_MOUSEBioGRID12202038 details