Entity Details

Primary name RPB4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15514
EntryNameRPB4_HUMAN
FullNameDNA-directed RNA polymerase II subunit RPB4
TaxID9606
Evidenceevidence at protein level
Length142
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesPOLR2D

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000398 mRNA splicing, via spliceosome
GO:0000932 P-body
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex
GO:0005829 cytosol
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006351 transcription, DNA-templated
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006370 7-methylguanosine mRNA capping
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0016070 RNA metabolic process
GO:0016607 nuclear speck
GO:0031369 translation initiation factor binding
GO:0031990 mRNA export from nucleus in response to heat stress
GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
GO:0042795 snRNA transcription by RNA polymerase II
GO:0045948 positive regulation of translational initiation
GO:0048239 negative regulation of DNA recombination at telomere
GO:0050434 positive regulation of viral transcription
GO:0060964 regulation of gene silencing by miRNA

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR005574 RNA polymerase subunit RPB4/RPC9FamilyFamily
IPR006590 RNA polymerase Rpb4/RPC9, coreDomainDomain
IPR010997 HRDC-like superfamilyFamilyHomologous superfamily
IPR038324 Rpb4/RPC9 superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
RPB4_HUMANMCAF1_MOUSEBioGRID10777215 details