Entity Details

Primary name PER1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15534
EntryNamePER1_HUMAN
FullNamePeriod circadian protein homolog 1
TaxID9606
Evidenceevidence at protein level
Length1290
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesPER1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001222 transcription corepressor binding
GO:0002028 regulation of sodium ion transport
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007623 circadian rhythm
GO:0009649 entrainment of circadian clock
GO:0010608 posttranscriptional regulation of gene expression
GO:0019900 kinase binding
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0032922 circadian regulation of gene expression
GO:0042634 regulation of hair cycle
GO:0042752 regulation of circadian rhythm
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043153 entrainment of circadian clock by photoperiod
GO:0043966 histone H3 acetylation
GO:0043967 histone H4 acetylation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046329 negative regulation of JNK cascade
GO:0051591 response to cAMP
GO:0070888 E-box binding
GO:0070932 histone H3 deacetylation
GO:0097167 circadian regulation of translation
GO:1900015 regulation of cytokine production involved in inflammatory response
GO:1900744 regulation of p38MAPK cascade
GO:2000323 negative regulation of glucocorticoid receptor signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR013655 PAS fold-3DomainDomain
IPR022728 Period circadian-like, C-terminalDomainDomain
IPR035965 PAS domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PER1_HUMANCRY2_MOUSEBioGRID, DIP23503662 details