Entity Details

Primary name RRP8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43159
EntryNameRRP8_HUMAN
FullNameRibosomal RNA-processing protein 8
TaxID9606
Evidenceevidence at protein level
Length456
SequenceStatuscomplete
DateCreated2005-04-26
DateModified2021-06-02

Ontological Relatives

GenesRRP8

GO terms

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GOName
GO:0000183 rDNA heterochromatin assembly
GO:0003723 RNA binding
GO:0005654 nucleoplasm
GO:0005677 chromatin silencing complex
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006364 rRNA processing
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0032259 methylation
GO:0033553 rDNA heterochromatin
GO:0035064 methylated histone binding
GO:0042149 cellular response to glucose starvation
GO:0046015 regulation of transcription by glucose
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR007823 Ribosomal RNA processing protein 8FamilyFamily
IPR023576 UbiE/COQ5 methyltransferase, conserved siteSiteConserved site
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily
IPR042036 Ribosomal RNA-processing protein 8, N-terminal domainFamilyHomologous superfamily

Diseases

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Interactions

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