Entity Details

Primary name ADA12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43184
EntryNameADA12_HUMAN
FullNameDisintegrin and metalloproteinase domain-containing protein 12
TaxID9606
Evidenceevidence at protein level
Length909
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesADAM12

GO terms

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GOName
GO:0004222 metalloendopeptidase activity
GO:0005576 extracellular region
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0007155 cell adhesion
GO:0007520 myoblast fusion
GO:0008237 metallopeptidase activity
GO:0016021 integral component of membrane
GO:0017124 SH3 domain binding
GO:0030198 extracellular matrix organization
GO:0045766 positive regulation of angiogenesis
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR000742 EGF-like domainDomainDomain
IPR001590 Peptidase M12B, ADAM/reprolysinDomainDomain
IPR001762 Disintegrin domainDomainDomain
IPR002870 Peptidase M12B, propeptideDomainDomain
IPR006586 ADAM, cysteine-rich domainDomainDomain
IPR018358 Disintegrin, conserved siteSiteConserved site
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR034027 Reprolysin domain, adamalysin-typeDomainDomain
IPR036436 Disintegrin domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink