Entity Details

Primary name PHF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43189
EntryNamePHF1_HUMAN
FullNamePHD finger protein 1
TaxID9606
Evidenceevidence at protein level
Length567
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesPHF1

GO terms

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GOName
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0006325 chromatin organization
GO:0006355 regulation of transcription, DNA-templated
GO:0006974 cellular response to DNA damage stimulus
GO:0035064 methylated histone binding
GO:0035861 site of double-strand break
GO:0042802 identical protein binding
GO:0045814 negative regulation of gene expression, epigenetic
GO:0046872 metal ion binding
GO:0061086 negative regulation of histone H3-K27 methylation
GO:0061087 positive regulation of histone H3-K27 methylation
GO:1990226 histone methyltransferase binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR002999 Tudor domainDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR025894 Polycomb-like MTF2 factor 2, C-terminal domainDomainDomain
IPR031202 PHD finger protein 1FamilyFamily
IPR040477 Lysine-specific demethylase 4, Tudor domainDomainDomain

Diseases

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Interactions

0 interactions

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