Entity Details

Primary name SUV91_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43463
EntryNameSUV91_HUMAN
FullNameHistone-lysine N-methyltransferase SUV39H1
TaxID9606
Evidenceevidence at protein level
Length412
SequenceStatuscomplete
DateCreated2002-11-15
DateModified2021-06-02

Ontological Relatives

GenesSUV39H1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000183 rDNA heterochromatin assembly
GO:0000775 chromosome, centromeric region
GO:0000792 heterochromatin
GO:0000794 condensed nuclear chromosome
GO:0000976 transcription cis-regulatory region binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005652 nuclear lamina
GO:0005654 nucleoplasm
GO:0005677 chromatin silencing complex
GO:0006325 chromatin organization
GO:0006364 rRNA processing
GO:0006974 cellular response to DNA damage stimulus
GO:0007049 cell cycle
GO:0008270 zinc ion binding
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0016032 viral process
GO:0018024 histone-lysine N-methyltransferase activity
GO:0030154 cell differentiation
GO:0033553 rDNA heterochromatin
GO:0034968 histone lysine methylation
GO:0036123 histone H3-K9 dimethylation
GO:0036124 histone H3-K9 trimethylation
GO:0042054 histone methyltransferase activity
GO:0042754 negative regulation of circadian rhythm
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046974 histone methyltransferase activity (H3-K9 specific)
GO:0047485 protein N-terminus binding
GO:0048511 rhythmic process
GO:0071456 cellular response to hypoxia

Subcellular Location

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Subcellular Location
Chromosome
Nucleus
Nucleus lamina

Domains

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DomainNameCategoryType
IPR000953 Chromo/chromo shadow domainDomainDomain
IPR001214 SET domainDomainDomain
IPR003616 Post-SET domainDomainDomain
IPR007728 Pre-SET domainDomainDomain
IPR011381 Histone H3-K9 methyltransferaseFamilyFamily
IPR016197 Chromo-like domain superfamilyFamilyHomologous superfamily
IPR023779 Chromo domain, conserved siteSiteConserved site
IPR023780 Chromo domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SUV91_HUMANCBX5_MOUSEBioGRID12242305 12565857 details
SUV91_HUMANHDAC9_MOUSEBioGRID12242305 details