Entity Details

Primary name CAH12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43570
EntryNameCAH12_HUMAN
FullNameCarbonic anhydrase 12
TaxID9606
Evidenceevidence at protein level
Length354
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesCA12

GO terms

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GOName
GO:0004089 carbonate dehydratase activity
GO:0005886 plasma membrane
GO:0006730 one-carbon metabolic process
GO:0008270 zinc ion binding
GO:0015701 bicarbonate transport
GO:0016021 integral component of membrane
GO:0016836 hydro-lyase activity
GO:0055064 chloride ion homeostasis

Subcellular Location

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Subcellular Location
Cell membrane
Membrane

Domains

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DomainNameCategoryType
IPR001148 Alpha carbonic anhydrase domainDomainDomain
IPR018338 Carbonic anhydrase, alpha-class, conserved siteSiteConserved site
IPR018430 Carbonic anhydrase, CA-XIIFamilyFamily
IPR023561 Carbonic anhydrase, alpha-classFamilyFamily
IPR036398 Alpha carbonic anhydrase domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00562 BenzthiazideDrugbanksmall molecule
DB00774 HydroflumethiazideDrugbanksmall molecule
DB00819 AcetazolamideDrugbanksmall molecule
DB00909 ZonisamideDrugbanksmall molecule
DB08846 Ellagic acidDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink