Entity Details
| Primary name |
TLX2_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | O43763 |
| EntryName | TLX2_HUMAN |
| FullName | T-cell leukemia homeobox protein 2 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 284 |
| SequenceStatus | complete |
| DateCreated | 1999-07-15 |
| DateModified | 2021-06-02 |
GO terms
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| GO | Name |
| GO:0000785 | chromatin |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0001707 | mesoderm formation |
| GO:0005634 | nucleus |
| GO:0005737 | cytoplasm |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0043565 | sequence-specific DNA binding |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0048484 | enteric nervous system development |
| GO:0048513 | animal organ development |
| GO:0050774 | negative regulation of dendrite morphogenesis |
| GO:1990837 | sequence-specific double-stranded DNA binding |
Subcellular Location
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| Subcellular Location |
| Nucleus |
Domains
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| Domain | Name | Category | Type |
| IPR001356 | Homeobox domain | Domain | Domain |
| IPR009057 | Homeobox-like domain superfamily | Family | Homologous superfamily |
| IPR017970 | Homeobox, conserved site | Site | Conserved site |
| IPR020479 | Homeobox domain, metazoa | Domain | Domain |
| IPR042247 | T-cell leukemia homeobox protein 1/2/3 | Family | Family |
Interactions
0 interactions
| Interactor | Partner | Sources | Publications | Link |