Entity Details

Primary name LIAS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43766
EntryNameLIAS_HUMAN
FullNameLipoyl synthase, mitochondrial
TaxID9606
Evidenceevidence at transcript level
Length372
SequenceStatuscomplete
DateCreated2002-10-10
DateModified2021-06-02

Ontological Relatives

GenesLIAS

GO terms

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GOName
GO:0001843 neural tube closure
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006954 inflammatory response
GO:0006979 response to oxidative stress
GO:0009107 lipoate biosynthetic process
GO:0009249 protein lipoylation
GO:0016992 lipoate synthase activity
GO:0019752 carboxylic acid metabolic process
GO:0032496 response to lipopolysaccharide
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0102552 lipoyl synthase activity (acting on glycine-cleavage complex H protein
GO:0102553 lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR003698 Lipoyl synthaseFamilyFamily
IPR006638 Elp3/MiaB/NifBDomainDomain
IPR007197 Radical SAMDomainDomain
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR031691 Lipoyl synthase, N-terminalDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00166 Lipoic acidDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink