Entity Details

Primary name SPOP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43791
EntryNameSPOP_HUMAN
FullNameSpeckle-type POZ protein
TaxID9606
Evidenceevidence at protein level
Length374
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesSPOP

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0016607 nuclear speck
GO:0030162 regulation of proteolysis
GO:0031463 Cul3-RING ubiquitin ligase complex
GO:0031625 ubiquitin protein ligase binding
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process

Subcellular Location

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Subcellular Location
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000210 BTB/POZ domainDomainDomain
IPR002083 MATH/TRAF domainDomainDomain
IPR008974 TRAF-likeFamilyHomologous superfamily
IPR011333 SKP1/BTB/POZ domain superfamilyFamilyHomologous superfamily
IPR034089 SPOP, C-terminal BACK domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SPOP_HUMANXBP1_MOUSEBioGRID31296559 details