Entity Details

Primary name SMCA5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60264
EntryNameSMCA5_HUMAN
FullNameSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
TaxID9606
Evidenceevidence at protein level
Length1052
SequenceStatuscomplete
DateCreated2004-10-25
DateModified2021-06-02

Ontological Relatives

GenesSMARCA5

GO terms

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GOName
GO:0000183 rDNA heterochromatin assembly
GO:0000793 condensed chromosome
GO:0001650 fibrillar center
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005677 chromatin silencing complex
GO:0005829 cytosol
GO:0006302 double-strand break repair
GO:0006334 nucleosome assembly
GO:0006338 chromatin remodeling
GO:0006352 DNA-templated transcription, initiation
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008094 ATPase, acting on DNA
GO:0016584 nucleosome positioning
GO:0016589 NURF complex
GO:0016887 ATP hydrolysis activity
GO:0031213 RSF complex
GO:0031491 nucleosome binding
GO:0034080 CENP-A containing nucleosome assembly
GO:0043044 ATP-dependent chromatin remodeling
GO:0043231 intracellular membrane-bounded organelle
GO:0045815 positive regulation of gene expression, epigenetic
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0070615 nucleosome-dependent ATPase activity
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000330 SNF2, N-terminalDomainDomain
IPR001005 SANT/Myb domainDomainDomain
IPR001650 Helicase, C-terminalDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR015194 ISWI, HAND domainDomainDomain
IPR015195 SLIDE domainDomainDomain
IPR017884 SANT domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036306 ISWI, HAND domain superfamilyFamilyHomologous superfamily
IPR038718 SNF2-like, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02379 Beta-D-GlucoseDrugbanksmall molecule
DB02670 4-Deoxy-Alpha-D-GlucoseDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink