Entity Details

Primary name MGRN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60291
EntryNameMGRN1_HUMAN
FullNameE3 ubiquitin-protein ligase MGRN1
TaxID9606
Evidenceevidence at protein level
Length552
SequenceStatuscomplete
DateCreated2006-07-25
DateModified2021-06-02

Ontological Relatives

GenesMGRN1

GO terms

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GOName
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006513 protein monoubiquitination
GO:0008333 endosome to lysosome transport
GO:0016020 membrane
GO:0016567 protein ubiquitination
GO:0043231 intracellular membrane-bounded organelle
GO:0043951 negative regulation of cAMP-mediated signaling
GO:0045744 negative regulation of G protein-coupled receptor signaling pathway
GO:0045879 negative regulation of smoothened signaling pathway
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Early endosome
Nucleus

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink