Entity Details

Primary name DIAP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60610
EntryNameDIAP1_HUMAN
FullNameProtein diaphanous homolog 1
TaxID9606
Evidenceevidence at protein level
Length1272
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesDIAPH1

GO terms

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GOName
GO:0003723 RNA binding
GO:0003779 actin binding
GO:0005102 signaling receptor binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007010 cytoskeleton organization
GO:0007605 sensory perception of sound
GO:0008360 regulation of cell shape
GO:0030036 actin cytoskeleton organization
GO:0030041 actin filament polymerization
GO:0030667 secretory granule membrane
GO:0031267 small GTPase binding
GO:0032587 ruffle membrane
GO:0032886 regulation of microtubule-based process
GO:0035372 protein localization to microtubule
GO:0043312 neutrophil degranulation
GO:0044325 transmembrane transporter binding
GO:0051279 regulation of release of sequestered calcium ion into cytosol
GO:0051493 regulation of cytoskeleton organization
GO:0071420 cellular response to histamine
GO:0072686 mitotic spindle
GO:0101003 ficolin-1-rich granule membrane
GO:2000145 regulation of cell motility

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR010465 DRF autoregulatoryDomainDomain
IPR010472 Formin, FH3 domainDomainDomain
IPR010473 Formin, GTPase-binding domainDomainDomain
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR014767 Diaphanous autoregulatory (DAD) domainDomainDomain
IPR014768 Rho GTPase-binding/formin homology 3 (GBD/FH3) domainDomainDomain
IPR015425 Formin, FH2 domainDomainDomain
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR027653 Formin, protein diaphanous homologue 1FamilyFamily
IPR042201 Formin, FH2 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DIAP1_HUMANPPM1F_MOUSEMINT18230650 details