Entity Details

Primary name LPXN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60711
EntryNameLPXN_HUMAN
FullNameLeupaxin
TaxID9606
Evidenceevidence at protein level
Length386
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesLPXN

GO terms

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GOName
GO:0002102 podosome
GO:0003712 transcription coregulator activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0007155 cell adhesion
GO:0007162 negative regulation of cell adhesion
GO:0007165 signal transduction
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0016020 membrane
GO:0016607 nuclear speck
GO:0033628 regulation of cell adhesion mediated by integrin
GO:0034446 substrate adhesion-dependent cell spreading
GO:0042995 cell projection
GO:0043542 endothelial cell migration
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0050859 negative regulation of B cell receptor signaling pathway
GO:0065003 protein-containing complex assembly

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001781 Zinc finger, LIM-typeDomainDomain
IPR017305 Leupaxin/Paxillin/TGFB1I1FamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
LPXN_HUMANHXA1_MOUSEIntAct23088713 details