Entity Details

Primary name BRD4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60885
EntryNameBRD4_HUMAN
FullNameBromodomain-containing protein 4
TaxID9606
Evidenceevidence at protein level
Length1362
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesBRD4

GO terms

Show/Hide Table
GOName
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000794 condensed nuclear chromosome
GO:0002039 p53 binding
GO:0003682 chromatin binding
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006974 cellular response to DNA damage stimulus
GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
GO:0016032 viral process
GO:0019899 enzyme binding
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043922 negative regulation by host of viral transcription
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050727 regulation of inflammatory response
GO:0070577 lysine-acetylated histone binding
GO:0099122 RNA polymerase II C-terminal domain binding
GO:0106140 P-TEFb complex binding
GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain
GO:2000002 negative regulation of DNA damage checkpoint
GO:2001255 positive regulation of histone H3-K36 trimethylation

Subcellular Location

Show/Hide Table
Subcellular Location
Chromosome
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001487 BromodomainDomainDomain
IPR018359 Bromodomain, conserved siteSiteConserved site
IPR027353 NET domainDomainDomain
IPR031354 Bromodomain protein 4, C-terminalDomainDomain
IPR036427 Bromodomain-like superfamilyFamilyHomologous superfamily
IPR038336 NET domain superfamilyFamilyHomologous superfamily
IPR043508 Brdt, bromodomain, repeat IDomainDomain
IPR043509 Brdt, bromodomain, repeat IIDomainDomain

Diseases

Show/Hide Table

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink