Entity Details

Primary name NDUS2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75306
EntryNameNDUS2_HUMAN
FullNameNADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length463
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesNDUFS2

GO terms

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GOName
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005747 mitochondrial respiratory chain complex I
GO:0005759 mitochondrial matrix
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0006979 response to oxidative stress
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0009055 electron transfer activity
GO:0019826 oxygen sensor activity
GO:0022008 neurogenesis
GO:0031625 ubiquitin protein ligase binding
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0042063 gliogenesis
GO:0042775 mitochondrial ATP synthesis coupled electron transport
GO:0046872 metal ion binding
GO:0048038 quinone binding
GO:0051287 NAD binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0061351 neural precursor cell proliferation
GO:0071453 cellular response to oxygen levels

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR001135 NADH-quinone oxidoreductase, subunit DDomainDomain
IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved siteSiteConserved site
IPR022885 NAD(P)H-quinone oxidoreductase subunit D/HFamilyFamily
IPR029014 [NiFe]-hydrogenase, large subunitFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB00997 DoxorubicinDrugbanksmall molecule

Interactions

0 interactions

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