Entity Details

Primary name GLRA3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75311
EntryNameGLRA3_HUMAN
FullNameGlycine receptor subunit alpha-3
TaxID9606
Evidenceevidence at protein level
Length464
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesGLRA3

GO terms

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GOName
GO:0004888 transmembrane signaling receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0007218 neuropeptide signaling pathway
GO:0007268 chemical synaptic transmission
GO:0016594 glycine binding
GO:0016934 extracellularly glycine-gated chloride channel activity
GO:0016935 glycine-gated chloride channel complex
GO:0022852 glycine-gated chloride ion channel activity
GO:0030425 dendrite
GO:0030594 neurotransmitter receptor activity
GO:0034220 ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0043005 neuron projection
GO:0043200 response to amino acid
GO:0043204 perikaryon
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0046872 metal ion binding
GO:0050877 nervous system process
GO:0051260 protein homooligomerization
GO:0060012 synaptic transmission, glycinergic
GO:1902476 chloride transmembrane transport

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Perikaryon

Domains

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DomainNameCategoryType
IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alphaFamilyFamily
IPR006029 Neurotransmitter-gated ion-channel transmembrane domainDomainDomain
IPR006201 Neurotransmitter-gated ion-channelFamilyFamily
IPR006202 Neurotransmitter-gated ion-channel ligand-binding domainDomainDomain
IPR008127 Glycine receptor alphaFamilyFamily
IPR008130 Glycine receptor alpha3FamilyFamily
IPR018000 Neurotransmitter-gated ion-channel, conserved siteSiteConserved site
IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamilyFamilyHomologous superfamily
IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00145 GlycineDrugbanksmall molecule
DB00431 LindaneDrugbanksmall molecule
DB00466 PicrotoxinDrugbanksmall molecule
DB00602 IvermectinDrugbanksmall molecule
DB01043 MemantineDrugbanksmall molecule
DB01956 TaurineDrugbanksmall molecule
DB09061 CannabidiolDrugbanksmall molecule
DB14009 Medical CannabisDrugbankbiotech
DB14011 NabiximolsDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink