Entity Details

Primary name NCOR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75376
EntryNameNCOR1_HUMAN
FullNameNuclear receptor corepressor 1
TaxID9606
Evidenceevidence at protein level
Length2440
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesNCOR1

GO terms

Show/Hide Table
GOName
GO:0000118 histone deacetylase complex
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006325 chromatin organization
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0007623 circadian rhythm
GO:0016020 membrane
GO:0017053 transcription repressor complex
GO:0019216 regulation of lipid metabolic process
GO:0030522 intracellular receptor signaling pathway
GO:0042826 histone deacetylase binding
GO:0045475 locomotor rhythm
GO:0045820 negative regulation of glycolytic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045922 negative regulation of fatty acid metabolic process
GO:0046329 negative regulation of JNK cascade
GO:0046966 thyroid hormone receptor binding
GO:0051225 spindle assembly
GO:0060766 negative regulation of androgen receptor signaling pathway
GO:0072686 mitotic spindle
GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001005 SANT/Myb domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017884 SANT domainDomainDomain
IPR031557 N-CoR, GPS2-interacting domainDomainDomain

Diseases

Show/Hide Table

Interactions

3 interactions