Entity Details

Primary name CISY_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75390
EntryNameCISY_HUMAN
FullNameCitrate synthase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length466
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesCS

GO terms

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GOName
GO:0003723 RNA binding
GO:0004108 citrate (Si)-synthase activity
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005975 carbohydrate metabolic process
GO:0006099 tricarboxylic acid cycle
GO:0006101 citrate metabolic process
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR002020 Citrate synthaseFamilyFamily
IPR010109 Citrate synthase, eukaryotic-typeFamilyFamily
IPR016142 Citrate synthase-like, large alpha subdomainFamilyHomologous superfamily
IPR016143 Citrate synthase-like, small alpha subdomainFamilyHomologous superfamily
IPR019810 Citrate synthase active siteSiteActive site
IPR036969 Citrate synthase superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01969 Trifluoroacetonyl coenzyme ADrugbanksmall molecule
DB01992 Coenzyme ADrugbanksmall molecule
DB02637 Oxaloacetate IonDrugbanksmall molecule
DB03182 alpha-Fluoro-carboxymethyldethia coenzyme A complexDrugbanksmall molecule
DB03499 D-Malic acidDrugbanksmall molecule
DB04230 Nitromethyldethia coenzyme ADrugbanksmall molecule
DB04272 Citric acidDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CISY_HUMANHSPB1_MOUSEBioGRID10383393 details