Entity Details

Primary name E2F6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75461
EntryNameE2F6_HUMAN
FullNameTranscription factor E2F6
TaxID9606
Evidenceevidence at protein level
Length281
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesE2F6

GO terms

Show/Hide Table
GOName
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0070317 negative regulation of G0 to G1 transition
GO:0071339 MLL1 complex
GO:0090575 RNA polymerase II transcription regulator complex

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR003316 E2F/DP family, winged-helix DNA-binding domainDomainDomain
IPR015633 E2F FamilyFamilyFamily
IPR015635 Transcription factor E2F6FamilyFamily
IPR032198 E2F transcription factor, CC-MB domainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037241 E2F-DP heterodimerization regionFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

4 interactions