Entity Details

Primary name EED_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75530
EntryNameEED_HUMAN
FullNamePolycomb protein EED
TaxID9606
Evidenceevidence at protein level
Length441
SequenceStatuscomplete
DateCreated2008-07-22
DateModified2021-06-02

Ontological Relatives

GenesEED

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol
GO:0006342 chromatin silencing
GO:0019058 viral life cycle
GO:0035098 ESC/E(Z) complex
GO:0042054 histone methyltransferase activity
GO:0042802 identical protein binding
GO:0045814 negative regulation of gene expression, epigenetic
GO:0045892 negative regulation of transcription, DNA-templated
GO:0070317 negative regulation of G0 to G1 transition
GO:0070734 histone H3-K27 methylation

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily
IPR037352 Polycomb protein EEDFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
EED_HUMANNSMA2_MOUSEDIP20080539 details
EED_HUMANTRPM7_MOUSEIntAct24855944 details