Entity Details

Primary name FOXH1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75593
EntryNameFOXH1_HUMAN
FullNameForkhead box protein H1
TaxID9606
Evidenceevidence at protein level
Length365
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesFOXH1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001947 heart looping
GO:0003139 secondary heart field specification
GO:0003151 outflow tract morphogenesis
GO:0003215 cardiac right ventricle morphogenesis
GO:0003222 ventricular trabecula myocardium morphogenesis
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0019904 protein domain specific binding
GO:0032444 activin responsive factor complex
GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway
GO:0035054 embryonic heart tube anterior/posterior pattern specification
GO:0035909 aorta morphogenesis
GO:0043425 bHLH transcription factor binding
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046332 SMAD binding
GO:0048318 axial mesoderm development
GO:0050681 androgen receptor binding
GO:0060766 negative regulation of androgen receptor signaling pathway
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0071345 cellular response to cytokine stimulus
GO:1900164 nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001766 Fork head domainDomainDomain
IPR030456 Fork head domain conserved site 2SiteConserved site
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink