Entity Details

Primary name KBL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75600
EntryNameKBL_HUMAN
FullName2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length419
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesGCAT

GO terms

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GOName
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0006520 cellular amino acid metabolic process
GO:0008890 glycine C-acetyltransferase activity
GO:0009058 biosynthetic process
GO:0016607 nuclear speck
GO:0019518 L-threonine catabolic process to glycine
GO:0030170 pyridoxal phosphate binding

Subcellular Location

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Subcellular Location
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding siteSiteBinding site
IPR004839 Aminotransferase, class I/classIIDomainDomain
IPR011282 2-amino-3-ketobutyrate coenzyme A ligaseFamilyFamily
IPR015421 Pyridoxal phosphate-dependent transferase, major domainFamilyHomologous superfamily
IPR015422 Pyridoxal phosphate-dependent transferase, small domainFamilyHomologous superfamily
IPR015424 Pyridoxal phosphate-dependent transferaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00114 Pyridoxal phosphateDrugbanksmall molecule
DB00145 GlycineDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink