Entity Details

Primary name MYCN_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP03966
EntryNameMYCN_MOUSE
FullNameN-myc proto-oncogene protein
TaxID10090
Evidenceevidence at transcript level
Length462
SequenceStatuscomplete
DateCreated1986-10-23
DateModified2021-06-02

Ontological Relatives

GenesMycn

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001502 cartilage condensation
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010942 positive regulation of cell death
GO:0019900 kinase binding
GO:0030324 lung development
GO:0042733 embryonic digit morphogenesis
GO:0045607 regulation of inner ear auditory receptor cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0048704 embryonic skeletal system morphogenesis
GO:0048712 negative regulation of astrocyte differentiation
GO:0048754 branching morphogenesis of an epithelial tube
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000378 negative regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002418 Transcription regulator MycFamilyFamily
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR012682 Transcription regulator Myc, N-terminalDomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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