Entity Details

Primary name WFS1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO76024
EntryNameWFS1_HUMAN
FullNameWolframin
TaxID9606
Evidenceevidence at protein level
Length890
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesWFS1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001822 kidney development
GO:0003091 renal water homeostasis
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
GO:0006983 ER overload response
GO:0007601 visual perception
GO:0007605 sensory perception of sound
GO:0022417 protein maturation by protein folding
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030425 dendrite
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0031398 positive regulation of protein ubiquitination
GO:0031625 ubiquitin protein ligase binding
GO:0032469 endoplasmic reticulum calcium ion homeostasis
GO:0034976 response to endoplasmic reticulum stress
GO:0036498 IRE1-mediated unfolded protein response
GO:0042593 glucose homeostasis
GO:0043069 negative regulation of programmed cell death
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043524 negative regulation of neuron apoptotic process
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0045927 positive regulation of growth
GO:0050821 protein stabilization
GO:0050877 nervous system process
GO:0051117 ATPase binding
GO:0051247 positive regulation of protein metabolic process
GO:0051928 positive regulation of calcium ion transport
GO:0055074 calcium ion homeostasis
GO:1903892 negative regulation of ATF6-mediated unfolded protein response
GO:2000675 negative regulation of type B pancreatic cell apoptotic process

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR026208 WolframinFamilyFamily
IPR026209 Wolframin familyFamilyFamily

Diseases

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Interactions

0 interactions

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