Entity Details

Primary name RECQ5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94762
EntryNameRECQ5_HUMAN
FullNameATP-dependent DNA helicase Q5
TaxID9606
Evidenceevidence at protein level
Length991
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesRECQL5

GO terms

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GOName
GO:0000278 mitotic cell cycle
GO:0000724 double-strand break repair via homologous recombination
GO:0000993 RNA polymerase II complex binding
GO:0003676 nucleic acid binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006259 DNA metabolic process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0009378 four-way junction helicase activity
GO:0016591 RNA polymerase II, holoenzyme
GO:0032508 DNA duplex unwinding
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter
GO:0035690 cellular response to drug
GO:0042802 identical protein binding
GO:0043138 3'-5' DNA helicase activity
GO:0051301 cell division
GO:0051304 chromosome separation
GO:0072757 cellular response to camptothecin
GO:1990414 replication-born double-strand break repair via sister chromatid exchange
GO:2000042 negative regulation of double-strand break repair via homologous recombination

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001650 Helicase, C-terminalDomainDomain
IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved siteSiteConserved site
IPR004589 DNA helicase, ATP-dependent, RecQ typeFamilyFamily
IPR010716 RecQ helicase-like 5DomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domainDomainDomain

Diseases

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Interactions

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