Entity Details

Primary name MTA2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94776
EntryNameMTA2_HUMAN
FullNameMetastasis-associated protein MTA2
TaxID9606
Evidenceevidence at protein level
Length668
SequenceStatuscomplete
DateCreated2003-02-28
DateModified2021-06-02

Ontological Relatives

GenesMTA2

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006306 DNA methylation
GO:0006333 chromatin assembly or disassembly
GO:0008270 zinc ion binding
GO:0010762 regulation of fibroblast migration
GO:0016020 membrane
GO:0016575 histone deacetylation
GO:0016581 NuRD complex
GO:0032991 protein-containing complex
GO:0042826 histone deacetylase binding
GO:0043044 ATP-dependent chromatin remodeling
GO:0043565 sequence-specific DNA binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1901796 regulation of signal transduction by p53 class mediator

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000679 Zinc finger, GATA-typeDomainDomain
IPR000949 ELM2 domainDomainDomain
IPR001005 SANT/Myb domainDomainDomain
IPR001025 Bromo adjacent homology (BAH) domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017884 SANT domainDomainDomain
IPR035170 Metastasis-associated protein MTA1, R1 domainDomainDomain
IPR037964 Metastasis-associated protein MTA2FamilyFamily
IPR040138 Mesoderm induction early response protein/metastasis-associated proteinFamilyFamily
IPR043151 Bromo adjacent homology (BAH) domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
MTA2_HUMANFOG1_MOUSEIntAct19654328 details
MTA2_HUMANZN521_MOUSEBioGRID21173110 details