Entity Details

Primary name GFAP_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP03995
EntryNameGFAP_MOUSE
FullNameGlial fibrillary acidic protein
TaxID10090
Evidenceevidence at protein level
Length430
SequenceStatuscomplete
DateCreated1986-10-23
DateModified2021-06-02

Ontological Relatives

GenesGfap

GO terms

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GOName
GO:0005178 integrin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005882 intermediate filament
GO:0006886 intracellular protein transport
GO:0009611 response to wounding
GO:0010467 gene expression
GO:0010625 positive regulation of Schwann cell proliferation
GO:0010977 negative regulation of neuron projection development
GO:0014002 astrocyte development
GO:0016020 membrane
GO:0019900 kinase binding
GO:0030198 extracellular matrix organization
GO:0031102 neuron projection regeneration
GO:0042802 identical protein binding
GO:0042995 cell projection
GO:0043209 myelin sheath
GO:0044297 cell body
GO:0045103 intermediate filament-based process
GO:0045109 intermediate filament organization
GO:0045111 intermediate filament cytoskeleton
GO:0051580 regulation of neurotransmitter uptake
GO:0060020 Bergmann glial cell differentiation
GO:0060252 positive regulation of glial cell proliferation
GO:0060291 long-term synaptic potentiation
GO:0070779 D-aspartate import across plasma membrane
GO:0097386 glial cell projection
GO:0097449 astrocyte projection
GO:0097450 astrocyte end-foot
GO:0098574 cytoplasmic side of lysosomal membrane
GO:1904714 regulation of chaperone-mediated autophagy

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR006821 Intermediate filament head, DNA-binding domainDomainDomain
IPR018039 Intermediate filament protein, conserved siteSiteConserved site
IPR027701 Glial fibrillary acidic proteinFamilyFamily
IPR039008 Intermediate filament, rod domainDomainDomain

Diseases

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