Entity Details

Primary name K2C1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP04104
EntryNameK2C1_MOUSE
FullNameKeratin, type II cytoskeletal 1
TaxID10090
Evidenceevidence at protein level
Length637
SequenceStatuscomplete
DateCreated1986-11-01
DateModified2021-06-02

Ontological Relatives

GenesKrt1

GO terms

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GOName
GO:0001533 cornified envelope
GO:0001867 complement activation, lectin pathway
GO:0016020 membrane
GO:0018149 peptide cross-linking
GO:0030246 carbohydrate binding
GO:0030280 structural constituent of skin epidermis
GO:0045095 keratin filament
GO:0046982 protein heterodimerization activity
GO:0050728 negative regulation of inflammatory response
GO:0051290 protein heterotetramerization
GO:0061436 establishment of skin barrier
GO:0062023 collagen-containing extracellular matrix

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003054 Keratin, type IIFamilyFamily
IPR018039 Intermediate filament protein, conserved siteSiteConserved site
IPR032444 Keratin type II headDomainDomain
IPR032449 Keratin type II cytoskeletal 1, tailDomainDomain
IPR039008 Intermediate filament, rod domainDomainDomain

Diseases

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Interactions

3 interactions