Entity Details

Primary name UBP19_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94966
EntryNameUBP19_HUMAN
FullNameUbiquitin carboxyl-terminal hydrolase 19
TaxID9606
Evidenceevidence at protein level
Length1318
SequenceStatuscomplete
DateCreated2001-06-20
DateModified2021-06-02

Ontological Relatives

GenesUSP19

GO terms

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GOName
GO:0004843 thiol-dependent deubiquitinase
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0016021 integral component of membrane
GO:0016579 protein deubiquitination
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0031625 ubiquitin protein ligase binding
GO:0031647 regulation of protein stability
GO:0034976 response to endoplasmic reticulum stress
GO:0046872 metal ion binding
GO:0048642 negative regulation of skeletal muscle tissue development
GO:0050821 protein stabilization
GO:0051879 Hsp90 protein binding
GO:0090068 positive regulation of cell cycle process
GO:1900037 regulation of cellular response to hypoxia
GO:1901799 negative regulation of proteasomal protein catabolic process
GO:1904292 regulation of ERAD pathway
GO:1990380 Lys48-specific deubiquitinase activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolaseDomainDomain
IPR002893 Zinc finger, MYND-typeDomainDomain
IPR007052 CS domainDomainDomain
IPR008978 HSP20-like chaperoneFamilyHomologous superfamily
IPR018200 Ubiquitin specific protease, conserved siteSiteConserved site
IPR028889 Ubiquitin specific protease domainDomainDomain
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
UBP19_HUMANHACD3_MOUSEIntAct25036637 details