Entity Details

Primary name TPX2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionA2APB8
EntryNameTPX2_MOUSE
FullNameTargeting protein for Xklp2
TaxID10090
Evidenceevidence at protein level
Length745
SequenceStatuscomplete
DateCreated2010-03-23
DateModified2021-06-02

Ontological Relatives

GenesTpx2

GO terms

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GOName
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005818 aster
GO:0005819 spindle
GO:0005880 nuclear microtubule
GO:0006915 apoptotic process
GO:0007020 microtubule nucleation
GO:0007026 negative regulation of microtubule depolymerization
GO:0008017 microtubule binding
GO:0015630 microtubule cytoskeleton
GO:0019901 protein kinase binding
GO:0030295 protein kinase activator activity
GO:0032147 activation of protein kinase activity
GO:0043203 axon hillock
GO:0045171 intercellular bridge
GO:0051225 spindle assembly
GO:0051301 cell division
GO:0060236 regulation of mitotic spindle organization
GO:0061676 importin-alpha family protein binding
GO:0072686 mitotic spindle
GO:0090307 mitotic spindle assembly

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR009675 TPX2FamilyFamily
IPR015128 Aurora-A bindingDomainDomain
IPR027329 TPX2, C-terminalDomainDomain
IPR027330 TPX2 central domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TPX2_MOUSEFBW1A_MOUSEBioGRID24115035 details