Entity Details

Primary name EPN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95208
EntryNameEPN2_HUMAN
FullNameEpsin-2
TaxID9606
Evidenceevidence at protein level
Length641
SequenceStatuscomplete
DateCreated2004-01-16
DateModified2021-06-02

Ontological Relatives

GenesEPN2

GO terms

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GOName
GO:0005543 phospholipid binding
GO:0005768 endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006897 endocytosis
GO:0030125 clathrin vesicle coat
GO:0030128 clathrin coat of endocytic vesicle
GO:0030276 clathrin binding
GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0043231 intracellular membrane-bounded organelle
GO:0045296 cadherin binding
GO:0045747 positive regulation of Notch signaling pathway
GO:0061024 membrane organization
GO:1903671 negative regulation of sprouting angiogenesis

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR003903 Ubiquitin interacting motifSiteConserved site
IPR008942 ENTH/VHSFamilyHomologous superfamily
IPR013809 ENTH domainDomainDomain
IPR027319 Epsin-2, metazoaFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
EPN2_HUMANEPS15_MOUSEBioGRID9303539 details
EPN2_HUMANEP15R_MOUSEBioGRID9303539 details