Entity Details

Primary name VAPB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95292
EntryNameVAPB_HUMAN
FullNameVesicle-associated membrane protein-associated protein B/C
TaxID9606
Evidenceevidence at protein level
Length243
SequenceStatuscomplete
DateCreated2002-11-01
DateModified2021-06-02

Ontological Relatives

GenesVAPB

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006874 cellular calcium ion homeostasis
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007029 endoplasmic reticulum organization
GO:0008017 microtubule binding
GO:0016021 integral component of membrane
GO:0019048 modulation by virus of host process
GO:0019899 enzyme binding
GO:0030148 sphingolipid biosynthetic process
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0033149 FFAT motif binding
GO:0036498 IRE1-mediated unfolded protein response
GO:0042803 protein homodimerization activity
GO:0044790 negative regulation by host of viral release from host cell
GO:0044791 positive regulation by host of viral release from host cell
GO:0044828 negative regulation by host of viral genome replication
GO:0044829 positive regulation by host of viral genome replication
GO:0044830 modulation by host of viral RNA genome replication
GO:0045070 positive regulation of viral genome replication
GO:0045296 cadherin binding
GO:0046725 negative regulation by virus of viral protein levels in host cell
GO:0046982 protein heterodimerization activity
GO:0048487 beta-tubulin binding
GO:0061817 endoplasmic reticulum-plasma membrane tethering
GO:0090114 COPII-coated vesicle budding
GO:0090158 endoplasmic reticulum membrane organization

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR000535 Major sperm protein (MSP) domainDomainDomain
IPR008962 PapD-like superfamilyFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016763 Vesicle-associated membrane-protein-associated proteinFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
VAPB_HUMANEPHA4_MOUSEBioGRID, IntAct18555774 details