Entity Details

Primary name BAG3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95817
EntryNameBAG3_HUMAN
FullNameBAG family molecular chaperone regulator 3
TaxID9606
Evidenceevidence at protein level
Length575
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesBAG3

GO terms

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GOName
GO:0000045 autophagosome assembly
GO:0000774 adenyl-nucleotide exchange factor activity
GO:0001725 stress fiber
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006457 protein folding
GO:0007420 brain development
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0010664 negative regulation of striated muscle cell apoptotic process
GO:0016020 membrane
GO:0016235 aggresome
GO:0021510 spinal cord development
GO:0030018 Z disc
GO:0031072 heat shock protein binding
GO:0034605 cellular response to heat
GO:0034620 cellular response to unfolded protein
GO:0042307 positive regulation of protein import into nucleus
GO:0043005 neuron projection
GO:0043066 negative regulation of apoptotic process
GO:0044877 protein-containing complex binding
GO:0045296 cadherin binding
GO:0045505 dynein intermediate chain binding
GO:0046716 muscle cell cellular homeostasis
GO:0046827 positive regulation of protein export from nucleus
GO:0050821 protein stabilization
GO:0051087 chaperone binding
GO:0061684 chaperone-mediated autophagy
GO:0070842 aggresome assembly
GO:0071260 cellular response to mechanical stimulus
GO:0072321 obsolete chaperone-mediated protein transport
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress
GO:0098840 protein transport along microtubule
GO:0101031 chaperone complex
GO:1900034 regulation of cellular response to heat
GO:1903215 negative regulation of protein targeting to mitochondrion
GO:1905337 positive regulation of aggrephagy

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001202 WW domainDomainDomain
IPR003103 BAG domainDomainDomain
IPR036020 WW domain superfamilyFamilyHomologous superfamily
IPR036533 BAG domain superfamilyFamilyHomologous superfamily
IPR039773 Molecular chaperone regulator BAGFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
BAG3_HUMANUBP19_MOUSEIntAct25036637 details