Entity Details

Primary name TBX6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95947
EntryNameTBX6_HUMAN
FullNameT-box transcription factor TBX6
TaxID9606
Evidenceevidence at protein level
Length436
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesTBX6

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001707 mesoderm formation
GO:0001708 cell fate specification
GO:0001947 heart looping
GO:0003205 cardiac chamber development
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007417 central nervous system development
GO:0007498 mesoderm development
GO:0008284 positive regulation of cell population proliferation
GO:0009653 anatomical structure morphogenesis
GO:0010977 negative regulation of neuron projection development
GO:0014043 negative regulation of neuron maturation
GO:0023019 signal transduction involved in regulation of gene expression
GO:0032525 somite rostral/caudal axis specification
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001699 Transcription factor, T-boxFamilyFamily
IPR002070 Transcription factor, BrachyuryFamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR018186 Transcription factor, T-box, conserved siteSiteConserved site
IPR036960 T-box superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink