Entity Details

Primary name MBD3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95983
EntryNameMBD3_HUMAN
FullNameMethyl-CpG-binding domain protein 3
TaxID9606
Evidenceevidence at protein level
Length291
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesMBD3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000792 heterochromatin
GO:0001701 in utero embryonic development
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006346 DNA methylation-dependent heterochromatin assembly
GO:0007420 brain development
GO:0007507 heart development
GO:0007568 aging
GO:0008327 methyl-CpG binding
GO:0009888 tissue development
GO:0016573 histone acetylation
GO:0016581 NuRD complex
GO:0031667 response to nutrient levels
GO:0032355 response to estradiol
GO:0032991 protein-containing complex
GO:0043044 ATP-dependent chromatin remodeling
GO:0044030 regulation of DNA methylation
GO:0048568 embryonic organ development
GO:1901796 regulation of signal transduction by p53 class mediator

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001739 Methyl-CpG DNA bindingDomainDomain
IPR016177 DNA-binding domain superfamilyFamilyHomologous superfamily
IPR025884 Methyl-CpG binding protein 2/3, C-terminal domainDomainDomain
IPR032343 Methyl-CpG-binding domain protein 2/3, p55-binding regionDomainDomain
IPR037965 Methyl-CpG-binding domain protein 3FamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
MBD3_HUMANMECOM_MOUSEMINT, UniProt18500823 30462309 details