Entity Details

Primary name TOP3B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95985
EntryNameTOP3B_HUMAN
FullNameDNA topoisomerase 3-beta-1
TaxID9606
Evidenceevidence at protein level
Length862
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesTOP3B

GO terms

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GOName
GO:0000793 condensed chromosome
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003916 DNA topoisomerase activity
GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity
GO:0005634 nucleus
GO:0006265 DNA topological change
GO:0007059 chromosome segregation

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000380 DNA topoisomerase, type IAFamilyFamily
IPR003601 DNA topoisomerase, type IA, domain 2DomainDomain
IPR003602 DNA topoisomerase, type IA, DNA-binding domainDomainDomain
IPR006171 TOPRIM domainDomainDomain
IPR013497 DNA topoisomerase, type IA, centralDomainDomain
IPR013824 DNA topoisomerase, type IA, central region, subdomain 1FamilyHomologous superfamily
IPR013825 DNA topoisomerase, type IA, central region, subdomain 2FamilyHomologous superfamily
IPR013826 DNA topoisomerase, type IA, central region, subdomain 3FamilyHomologous superfamily
IPR023405 DNA topoisomerase, type IA, core domainFamilyHomologous superfamily
IPR023406 DNA topoisomerase, type IA, active siteSiteActive site
IPR034144 DNA topoisomerase 3-like, TOPRIM domainDomainDomain

Diseases

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Interactions

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