Entity Details

Primary name PAK4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO96013
EntryNamePAK4_HUMAN
FullNameSerine/threonine-protein kinase PAK 4
TaxID9606
Evidenceevidence at protein level
Length591
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesPAK4

GO terms

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GOName
GO:0001558 regulation of cell growth
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005912 adherens junction
GO:0005925 focal adhesion
GO:0006915 apoptotic process
GO:0007010 cytoskeleton organization
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0016477 cell migration
GO:0031098 stress-activated protein kinase signaling cascade
GO:0032147 activation of protein kinase activity
GO:0045766 positive regulation of angiogenesis
GO:0060996 dendritic spine development
GO:0071407 cellular response to organic cyclic compound
GO:0098641 cadherin binding involved in cell-cell adhesion
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000352 negative regulation of endothelial cell apoptotic process

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000095 CRIB domainDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR033923 p21 activated kinase binding domainDomainDomain
IPR036936 CRIB domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink